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Pirkko L Härkönen Selected Research

Fibroblast Growth Factor 8

11/2010Stromal activation associated with development of prostate cancer in prostate-targeted fibroblast growth factor 8b transgenic mice.
10/2010Fast growth associated with aberrant vasculature and hypoxia in fibroblast growth factor 8b (FGF8b) over-expressing PC-3 prostate tumour xenografts.
3/2010Fibroblast growth factor 8 increases breast cancer cell growth by promoting cell cycle progression and by protecting against cell death.
7/2009FGF-8b induces growth and rich vascularization in an orthotopic PC-3 model of prostate cancer.
6/2007Role of fibroblast growth factor 8 in growth and progression of hormonal cancer.
7/2006Androgen and fibroblast growth factor 8 (FGF8) downregulation of thrombospondin 1 (TSP1) in mouse breast cancer cells.

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Pirkko L Härkönen Research Topics

Disease

13Neoplasms (Cancer)
06/2019 - 04/2002
9Breast Neoplasms (Breast Cancer)
06/2019 - 04/2002
8Prostatic Neoplasms (Prostate Cancer)
08/2018 - 05/2002
6Neoplasm Metastasis (Metastasis)
08/2018 - 04/2002
3Osteoporosis
08/2018 - 12/2005
2Lymphatic Metastasis
03/2008 - 04/2002
2Osteosarcoma (Osteogenic Sarcoma)
05/2006 - 03/2003
2Bone Resorption
12/2005 - 05/2002
1Pain (Aches)
06/2019
1Bone Diseases (Bone Disease)
08/2018
1Sarcoma (Soft Tissue Sarcoma)
11/2010
1Hypoxia (Hypoxemia)
10/2010
1Necrosis
05/2007
1Neuroinflammatory Diseases
11/2006
1Adenocarcinoma
11/2004
1Inflammation (Inflammations)
11/2004
1Carcinogenesis
11/2004
1Metaplasia
11/2004
1Hyperplasia
01/2002

Drug/Important Bio-Agent (IBA)

6Fibroblast Growth Factor 8IBA
11/2010 - 07/2006
5Estrogens (Estrogen)FDA Link
06/2007 - 04/2002
4AndrogensIBA
06/2007 - 01/2002
3Diphosphonates (Bisphosphonates)IBA
08/2018 - 05/2002
3Alendronate (Alendronate Sodium)FDA LinkGeneric
08/2018 - 05/2002
3Hormones (Hormone)IBA
06/2007 - 04/2002
2Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA
06/2019 - 01/2012
2Androgen Receptors (Androgen Receptor)IBA
11/2010 - 12/2005
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2010 - 04/2002
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
06/2007 - 05/2006
2CytokinesIBA
05/2007 - 11/2006
2Testosterone (Sustanon)FDA Link
07/2006 - 12/2005
1AcidsIBA
06/2019
14- amino- 5- fluoro- 3- (5- (4- methylpiperazin- 1- yl)- 1H- benzimidazol- 2- yl)quinolin- 2(1H)- oneIBA
06/2019
1Deoxyglucose (2 Deoxy D glucose)IBA
06/2019
1NitrogenIBA
08/2018
1Actin Depolymerizing Factors (Cofilins)IBA
08/2018
1Adenosine (Adenocard)FDA LinkGeneric
12/2014
1Adenosine Diphosphate (ADP)IBA
12/2014
15'-Nucleotidase (5' Nucleotidase)IBA
12/2014
1purineIBA
12/2014
1Adenosine DeaminaseIBA
12/2014
1Adenosine Triphosphate (ATP)IBA
12/2014
1PurinesIBA
12/2014
1Purinergic P1 Receptors (Adenosine Receptor)IBA
12/2014
1NucleotidesIBA
12/2014
1NucleosidesIBA
12/2014
1Small Interfering RNA (siRNA)IBA
01/2012
1Fibroblast Growth Factors (Fibroblast Growth Factor)IBA
01/2012
1Facilitative Glucose Transport Proteins (Glucose Transporter)IBA
10/2010
12- (3- pyridinyl)- 1- hydroxyethylidene- 1,1- phosphonocarboxylic acidIBA
08/2010
1TransferasesIBA
08/2010
1Pharmaceutical PreparationsIBA
08/2010
1geranylgeranyltransferase type-I (protein geranylgeranyltransferase)IBA
08/2010
1Cell Cycle ProteinsIBA
03/2010
1Messenger RNA (mRNA)IBA
07/2009
1Progestins (Progestagens)IBA
06/2007
1SteroidsIBA
06/2007
1Growth Factor ReceptorsIBA
06/2007
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2007
1Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
05/2007
1Thrombospondin 1IBA
07/2006
1OsteocalcinIBA
05/2006
1Heparin (Liquaemin)FDA LinkGeneric
05/2006
1CollagenIBA
05/2006
1Neutralizing AntibodiesIBA
05/2006
1Flutamide (Eulexin)FDA LinkGeneric
12/2005
1Fulvestrant (Faslodex)FDA Link
12/2005
1Gallic AcidIBA
02/2005
1triphalaIBA
02/2005
1AcetoneIBA
02/2005
1PolyphenolsIBA
02/2005
1Therapeutic UsesIBA
11/2004
1Estrogen Receptor Modulators (Antiestrogen)IBA
11/2004
1Selective Estrogen Receptor Modulators (SERM)IBA
03/2003
1TamoxifenFDA LinkGeneric
03/2003
1Toremifene (Fareston)FDA Link
03/2003
1Estrogen ReceptorsIBA
03/2003
1Clodronic Acid (Clodronate)IBA
05/2002
1Mevalonic Acid (Mevalonate)IBA
05/2002
1AntibodiesIBA
04/2002
1Keratins (Keratin)IBA
04/2002
1Platelet Endothelial Cell Adhesion Molecule-1IBA
04/2002
1Trefoil Factor-1IBA
04/2002
1Hyaluronan ReceptorsIBA
04/2002
1Vascular Endothelial Growth Factor CIBA
04/2002

Therapy/Procedure

1Castration
11/2004
1Therapeutics
11/2004